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Most children with VATER should be able to manage the intellectual demands of school without too much difficulty. In addition to asking your doctor about VATER syndrome, you can find specialists through the National Center for Biotechnology Information or specialist pediatric hospitals like Cincinnati Children's.

Get diet and wellness tips to help your kids stay healthy and happy. Solomon BD. Orphanet J Rare Dis.

Yang L, Li S, Zhong L, Qiu L, Xie L, Chen L. VACTERL association complicated with multiple airway abnormalities: A case repor t. Medicine Baltimore.

Raam MS, Pineda-Alvarez DE, Hadley DW, Solomon BD. Long-term outcomes of adults with features of VACTERL association. Eur J Med Genet. Stevenson RE, Hunter AG.

Considering the embryopathogenesis of VACTERL association. Mol Syndromol. Castori M, Rinaldi R, Capocaccia P, Roggini M, Grammatico P.

VACTERL association and maternal diabetes: a possible causal relationship? Birth Defects Res Part A Clin Mol Teratol. Guthrie J. Prenatal diagnosis of VACTERL association.

J Diag Med Sonography. National Center for Advancing Translational Sciences. VACTERL association. Updated January 26, Table of Contents View All.

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An estimated 1 out of every 10, to 40, babies is born with this group of conditions. They believe the defects happen early in pregnancy. A combination of genes and environmental factors may be involved.

No single gene has been identified, but researchers have found a few chromosomal abnormalities and gene changes mutations related to the condition.

Sometimes more than one person in the same family will be affected. Up to 80 percent of people with VATER association have defects in the bones of their spine vertebrae.

These problems can include:. Between 60 and 90 percent of people with VATER association have a problem with their anus, such as:. These can include:.

Symptoms of heart problems include:. A fistula is an abnormal connection between the trachea windpipe and the esophagus the tube that carries food from the mouth to the stomach.

These two structures are not normally connected at all. It interferes with food passing from the throat to the stomach, diverting some food into the lungs.

Kidney defects can cause frequent urinary tract infections. Boys can also have a defect in which the opening of their penis is on the bottom, instead of at the tip hypospadias.

Up to 70 percent of babies with VACTERL have limb defects. Because VATER association is a cluster of conditions, no single test can diagnose it.

Doctors usually make the diagnosis based on clinical signs and symptoms. Babies with this condition have at least three VATER or VACTERL defects.

Treatment is based on what types of birth defects are involved. Surgery can fix many of the defects, including problems with the anal opening, bones of the spine, heart, and kidneys.

Often these procedures are done soon after the child is born. Because VATER association involves several body systems, a few different doctors treat it, including a:.

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